Holdsworth shifted to Stone Brothers Racing in 2012 from GRM, where he claimed two race wins and 14 top three finishes.
He burst onto the scene with a stunning win in the wet at Oran Park in 2007, before winning at Sydney Olympic Park in 2010 en route to a career-best seventh in the championship.
He remained with SBR when it became Erebus Motorsport in 2013, and won a race for the team in a Mercedes at Winton a year later.
That remained his final podium visit to his 2019 Sandown 500 third place, following four torrid seasons for Team 18 between 2015 and 2018.
His troubled Team 18 stint was punctuated by a shocking accident in Darwin, which sidelined him for a number of events due to fractures to his right knee, two ribs and pelvis.
The move to Tickford, which came amid Mark Winterbottom’s defection to Team 18, saw Holdsworth rediscover some of his best form as he clinched podiums at Sandown (2019) and Sydney Motorsport Park (2020).
Tickford also confirmed it will scale back to a three-car operation in 2021, with Jack Le Brocq taking over the #5 Truck Assist Ford Mustang.
The 2021 season will commence at the Mt Panorama 500 across February 26-28.